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LONDON (SHARECAST) - Pharmaceutical group Shire saw sales and earnings fall in the first quarter of 2010 as its ADHD treatment Adderall felt the impact of competition following the expiration of its exclusivity. Bullish talk from one of London's heavyweight brokers helped the FTSE 100 finish the week 4.2pc higher. Feb. 19 (Bloomberg) -- Shire Plc climbed the most in almost four months in London trading after unexpected royalties and rebates on the Adderall attention deficit pill helped the U.K. drugmaker to beat fourth-quarter profit estimates. Feb. 19 (Bloomberg) -- Shire Plc climbed the most in more than 10 months in London trading after unexpected royalties and rebates on the Adderall attention deficit pill helped the U.K. drugmaker to beat fourth-quarter profit estimates.